Mr. Olanrewaju Durujaye
Mr. Olanrewaju Durujaye graduated from the Biochemistry department of the Olabisi Onabanjo University, Ago Iwoye with a B,Sc in Biochemistry and Molecular Biology. He obtained a Masters Degree in Molecular Biology with a special research interest in Bioinformatics from the Biochemistry department of the University of Nigeria, Nsukka. All the years of his study, he tried to develop a good sense of research in his chosen field of study.
He has done his M.Sc. dissertation in the field of Comparative Genomics where he used a wide range of Web-Based Bioinformatics tools in the analysis of lipoxygenase in different species and strains of Aspergillus and Fusarium. He also carried out a research on the structure and function of Plasmodium falciparum Triosephosphate isomerase as a therapeutic option in antimalarial drug design which was presented at the Premiere Medicinal Plants Summit for West Africa, organized by the Bioscience Research Education and Advisory Centre. This was also published in the book of abstract.
He has a good number of publications on computer-aided drug design in different reputable international journals around the world eg: Binding Energy Prediction and Molecular Docking Studies of Falcarindiol and its Monosubstituted Analogues Against Aspergillus fumigatus Chitinase; The In Silico Pharmacokinetics, In-Silico Structure-Activity Relationship and Molecular Docking Studies of Monosubstitted 6-Gingerol against Streptococcus pneumoniae Phosphomevalonate Kinase, Genomic sequence analysis of Aspergillus fumigatus lipoxygenase: a causative agent of severe asthma and Review On Structure-Activity Relationship (Sar) Using Antimalarial Drug Design As A Case Study. Many others have been accepted and awaiting publication eg: A systematic Study on the Structure and Function of Plasmodium falciparum Triosephosphate isomerase as a Therapeutic Option in Antimalarial drug design, In-Silico Structure-Activity Relationship and Molecular Docking Study of Levofloxacin and its Monosubstitted Analogues against the Escherichia coli DNA Gyrase, Identification of Candidate Inhibitory Ligands from Allium cepa and Molecular Docking Against Trypanosma brucei Phosphoglycerate Kinase; The In-Silico Structure-Activity Relationship and Application of Translational Bioinformatics in Drug Interaction Research (Review).
He is currently carrying out a systemic study on the whole wheat consumption relationship with gluten-linked cardiovascular diseases and phytic acid-linked nutrient depletion; a research sponsored by the HoneyWell Flour Mill where some of the research objectives includes; sequencing the whole wheat gliadin gene, translating the gene to derive the amino acid sequence, determining the protein conserved domain(s), determination of the evolutionary relationship between gluten homologues and prediction of the protein antigenicity site(s) amongst others.
He has a sound knowledge of the application of advance Bioinformatics tools in the analysis of a wide range of genomic data. His competence also cuts across the application of basic software and programming languages used in the analysis of a large array of data in comparative genomics. Coupled with these is his ability to competently handle laboratory equipments necessary for a successful research in molecular biosciences.
He has also attended an extensive training course on the application of biotechniques to medicinal plants research. This course covered a wide range of laboratory practical on gene expression and regulation, DNA isolation, Polymerase Chain Reaction and gene amplification, Agarose gel electrophoresis, Restriction Fragment Length Polymorphism, DNA Barcoding, Animal cell culture, etc.
- Molecular Biology